Taking US60 for the majority of the route. US60 has the following junctions:

West end:	I‑10 at Brenda, AZ
	I‑10 / I‑17 at Phoenix, AZ  I‑25 at Socorro, NM  I-27 at Canyon, TX  I‑44 at Vinita, OK  I-24 / I-66 at Paducah, KY  I-65 at Louisville, KY  I-75 at Lexington, KY  I‑64 / I‑77 at Charleston, WV  I‑81 at Lexington, VA  I‑95 at Richmond, VA
East end:	5th Street at Virginia Beach, VA